Fig. 5From: Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activityA1541–43 are predicted to bind a pocket within the ERK1/2 protein. a Binding of A1541–43, EQW and Cedrelone within pocket A and B of ERK1/2. b Relative binding of Cedrelone and A1541 (b), Cedrelone and A1542 (c), Cedrelone and A1543 (d) within the pocket B and A of ERK1/2, respectively. e Properties of drug binding affinities to ERK1.2Back to article page