Fig. 3
From: Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity
Induction of megakaryocytic or erythroid differentiation in erythroleukemia cell line CB7 by A1541 and A1543. a-c Treatment of the erythroleukemic cell lines CB7 with A1541 and A1543 increases the percentage of CD71/TER119+ erythroid cells (a), but has no effect on percentage of CD41+ (b) and CD61+ (c) megakaryocytic cells after 24 h. Cedrelone had no effect on erythroid and megakaryocytic differentiation of CB7 cells (a-c)