Table 1 Parameters estimated for the LMM (Eq. 3) of the cisplatin dataset
From: The design, analysis and application of mouse clinical trials in oncology drug development
Fixed-Effect Parameters | Estimate* | p-value |
|---|---|---|
β0 (Intercept) | 5.2641 (0.0257) | 0 |
β1 (Day) | 0.0605 (0.0043) | 1.5E-43 |
β2 (Day × CancerTypeGA) | 0.0091 (0.0055) | 0.098 |
β3 (Day × CancerTypeLU) | 0.0297 (0.0071) | 2.8E-5 |
β4 (Day × Treatment) | −0.0282 (0.0031) | 1.2E-19 |
β5 (Day × CancerTypeGA × Treatment) | 0.0037 (0.0039) | 0.35 |
β6 (Day × CancerTypeLU × Treatment) | −0.0011 (0.0052) | 0.84 |