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Table 6 Multivariable Cox regression analysis for MKI67 low/high

From: Impact of molecular subtypes on the prediction of distant recurrence in estrogen receptor (ER) positive, human epidermal growth factor receptor 2 (HER2) negative breast cancer upon five years of endocrine therapy

  

Hazard Ratio

Parameter

Effect

Estimate

95% CIs

p-value

MKI67 Positive (high)

Positive

2.270

0.986–5.226

0.0541

T-stage

Increase by ‘+ 1’

2.273

1.274–4.052

0.0054

N-stage

Increase by ‘+ 1’

1.401

0.819–2.399

0.2187

Tumor grading

Increase by ‘+ 1’

2.111

0.814–5.478

0.1245