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Table 6 Multivariable Cox regression analysis for MKI67 low/high

From: Impact of molecular subtypes on the prediction of distant recurrence in estrogen receptor (ER) positive, human epidermal growth factor receptor 2 (HER2) negative breast cancer upon five years of endocrine therapy

   Hazard Ratio
Parameter Effect Estimate 95% CIs p-value
MKI67 Positive (high) Positive 2.270 0.986–5.226 0.0541
T-stage Increase by ‘+ 1’ 2.273 1.274–4.052 0.0054
N-stage Increase by ‘+ 1’ 1.401 0.819–2.399 0.2187
Tumor grading Increase by ‘+ 1’ 2.111 0.814–5.478 0.1245