Fig. 6

MiR-3613 regulates EGFR pathway genes in CAF induced A549 early EMT. a Number of DEmiRNAs at each time point between CAF and control treated A549 cells. b Transcripts per million (TPM) of miR-3613-3p in CAF treated and control A549 cells. ***, p < 0.001, Fisher’s exact test. c GO analysis of the biological process ontology of miR-3613 predicted targets. Top ten terms and corrected p-values were shown. d Predicted miR-3613-3p regulatory targets in the EGFR pathway from 3 to 24 h after CAF treatment. e Barplot showing the downregulation of miR-3613 targets after miR-3613 overexpression. **, p < 0.01, ***, p < 0.001; t-test