Fig. 5
From: The role of clonal communication and heterogeneity in breast cancer
DNA methylation profile of MDA-MB-231 clonal cell lines. a Heatmap of the most differentially methylated CpGs (delta ≥0.20) localized at promoter, CpG island and shore regions (12,201 CpGs). b-c Identification of genes whose expression changes could be explained by methylation differences: (b) downregulated vs hypermethylated and (c) upregulated vs hypomethylated. d Venn diagrams of methylation gene changes of selected clonal cell lines vs. MDA-MB-231. e-f Gene Ontology (e) and KEGG (f) with differentially methylated genes (delta ≥0.20) at promoter and CpG island and shore