Table 2 Multivariate Cox proportional hazards regression analyses for overall and cancer-specific mortality in patients with leiomyosarcoma or carcinosarcoma

 No treatment

reference

reference

reference

reference

 EBRT alone

0.90 (0.54, 1.51)

0.697

0.91 (0.51, 1.64)

0.760

0.72 (0.53, 0.99)

0.042

0.78 (0.54, 1.14)

0.199

 Brachytherapy alone

0.57 (0.14, 2.31)

0.429

0.47 (0.07, 3.38)

0.452

0.55 (0.37, 0.80)

0.002

0.51 (0.31, 0.84)

0.009

 Combination radiotherapy ^e

NA

NA

NA

NA

0.47 (0.29, 0.77)

0.003

0.53 (0.29, 0.95)

0.034

 < 60 years

reference

reference

 ≥ 60 years

1.55 (1.11, 2.18)

0.011

1.74 (1.27, 2.37)

0.001

 Stage I

reference

reference

reference

reference

 Stage II

1.82 (1.15, 2.89)

0.011

1.85 (1.09, 3.12)

0.022

1.06 (0.67, 1.69)

0.802

1.10 (0.61, 1.98)

0.758

 Stage III

3.07 (2.01, 4.69)

< 0.001

3.21 (2.02, 5.13)

< 0.001

2.36 (1.88, 2.97)

< 0.001

2.57 (1.93, 3.42)

< 0.001

 Grade 1

reference

 Grade 2

1.58 (0.18, 13.60)

0.679

 Grade 3

7.17 (0.97, 52.86)

0.053

 Undifferentiated/anaplastic

5.08 (0.69, 37.09)

0.110

  ≤ 50 mm

reference

reference

reference

  > 50 mm

2.98 (1.38, 6.45)

0.006

1.96 (1.50, 2.57)

< 0.001

2.07 (1.46, 2.93)

< 0.001

 No

reference

reference

 Yes

0.61 (0.47, 0.78)

< 0.001

0.61 (0.45, 0.84)

0.003