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Table 3 Clinicopathological parameters correlated to RELA fusions in intracranial ependymal tumors

From: Clinical significance of the histological and molecular characteristics of ependymal tumors: a single institution case series from China

 

RELA fusions present

P value

Age

 

0.002

 ≤ 18 years

13/21

 > 18 years

4/24

Gender

  

 Male

11/25

0.336

 Female

6/20

 

WHO grade

  

 Grade II

1/15

0.008

 Grade III

16/30

 

Cellularity

  

 low

1/5

0.047

 moderate

2/12

 

 high

11/19

 

Cellular atypia

  

 mild

1/9

0.029

 moderate

4/13

 

 severe

9/14

 

Vascular proliferation

  

 absent

3/19

0.003

 present

11/17

 

 Mitosis

  

 ≤ 5/2mm2

4/19

0.020

 > 5/2mm2

10/17

 

Necrosis

  

 absent

2/15

0.008

 present

12/21

 

Ki67 index

  

 ≤ 6%

2/23

<0.001

 > 6%

12/16

 

CCND1 amplification

  

 present

5/14

0.800

 absent

8/20

 
  1. *: Some cases were lost due to inadequate tissue for testing or other reasons
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BMC Cancer

ISSN: 1471-2407

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