From: Peripheral ganglia in healthy rats as target structures for the evaluation of PSMA imaging agents
n | SCG, SUVBW | SNR | Liver, SUVBW | Bone, SUVBW | |
---|---|---|---|---|---|
[18F]DCFPyL | 6 | 20.2 ± 5.8 | 6.7 ± 2.6 | 65.3 ± 21.7 | 12.4 ± 4.3 |
[18F]DCFPyL + 2-PMPA | 3 | 4.6 ± 1.8* | 3.7 ± 2.1 | 47.0 ± 7.7 | 6.1 ± 1.9 |
[Al18F]PSMA-11 | 3 | 36.8 ± 9.5* | 4.5 ± 1.4 | 15.5 ± 4.2* | 122.8 ± 50.1* |
[68Ga]PSMA-11 | 3 | 41.0 ± 3.4* | 4.5 ± 0.1 | 47.0 ± 10.4 | 18.5 ± 0.61 |
ANOVA main effect | F (3, 11)=24.8 p < 0.0001 | F (3, 11) =1.7 p = 0.2167 | F (3, 11) = 6.7 p = 0.0079 | F (3, 11) = 21.1 p < 0.0001 |