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Table 1 Accumulation of PSMA tracers in different tissues

From: Peripheral ganglia in healthy rats as target structures for the evaluation of PSMA imaging agents

 

n

SCG, SUVBW

SNR

Liver, SUVBW

Bone, SUVBW

[18F]DCFPyL

6

20.2 ± 5.8

6.7 ± 2.6

65.3 ± 21.7

12.4 ± 4.3

[18F]DCFPyL + 2-PMPA

3

4.6 ± 1.8*

3.7 ± 2.1

47.0 ± 7.7

6.1 ± 1.9

[Al18F]PSMA-11

3

36.8 ± 9.5*

4.5 ± 1.4

15.5 ± 4.2*

122.8 ± 50.1*

[68Ga]PSMA-11

3

41.0 ± 3.4*

4.5 ± 0.1

47.0 ± 10.4

18.5 ± 0.61

ANOVA main effect

 

F (3, 11)=24.8 p < 0.0001

F (3, 11) =1.7 p = 0.2167

F (3, 11) = 6.7 p = 0.0079

F (3, 11) = 21.1 p < 0.0001

  1. Abbreviations: SCG: superior cervical ganglion, SNR signal-to-noise ratio measured for SCG. *Significantly different from [18F]DCFPyL; p < 0.05 in Dunnett’s multiple comparison test