Skip to main content

Advertisement

Fig 3 | BMC Cancer

Fig 3

From: Knockdown of YAP inhibits growth in Hep-2 laryngeal cancer cells via epithelial-mesenchymal transition and the Wnt/β-catenin pathway

Fig 3

Silencing of YAP promotes cell apoptosis and induces cell cycle arrest. a Guava easyCyte12 was used to investigate differences in cell cycle (top panel) distribution following YAP silencing or overexpression in Hep-2. Silenced YAP drove G2/M arrest in control, YAP-NC, YAP-shRNA and YAP-shRNA+YAP-cDNA cell groups. In addition, when YAP knockdown Hep-2 cells overexpressed YAP, the G2/M phase distribution was decreased, **P < 0.01; b Apoptotic cells (medium panel) were analysed by Guava easyCyte12 via staining of annexin PE/7-AAD. The percentage of apoptotic cells is shown. **P < 0.01

Back to article page