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Table 3 Number and type of metastases in sentinel node and risk of metastases in non-sentinel node

From: Determinants for non-sentinel node metastases in primary invasive breast cancer: a population-based cohort study of 602 consecutive patients with sentinel node metastases

SN Category Total (n) Negative Non-SN (n) Positive Non-SN (n) Positive Non-SN (%) OR (95% CI) ORa (95% CI)
SN removed (n) 1 118 84 34 28.8 1.00 1.00
2 208 125 83 39.9 1.64 (1.01–2.66) 1.34 (0.77–2.31)
3 166 110 56 33.7 1.26 (0.75–2.10) 1.08 (0.61–1.93)
4 83 56 27 32.5 1.19 (0.65–2.19) 0.96 (0.48–1.90)
≥5 25 15 10 40.0 1.65 (0.67–4.03) 1.71 (0.65–4.53)
Unknown 2 1 1
Total 602 391 211  
Type of metastases in SNb Micro 186 159 27 14.5 1.00 1.00
Macro 414 232 182 43.9 4.62 (2.94–7.26) 4.91 (3.01–8.05)
Unknown 2 0 2
Total 602 391 211  
  1. aAdjusted for screening, age, menopause, tumour size, tumour type, histological grade, estrogen receptors, progesterone receptors, HER2, multifocality and lymphovascular invasion
  2. bIf both micro- and macro-metastases, classified as macro-metastases