Table 2 Recurrence risk according to pathological response, Neo-Bioscore and Clustered Neo-Bioscore
Neo-Bioscore | All patients | pCRc | non-pCR | |||
n = 310 | DFS-3y (CI95%)a | n = 43 | DFS-3y (CI95%) | n = 267 | DFS-3y (CI95%) | |
0 | 1 (0.3%) | 1.00 | 0 | 1.00 | 1 (0.4%) | 1.00 |
1 | 18 (5.8%) | 1.00 | 5 (11.6%) | 1.00 | 13 (4.9%) | 1.00 |
2 | 47 (15.2%) | 0.88 (0.81–0.95) | 12 (27.9%) | 0.89 (0.79–0.99) | 35 (13.1%) | 0.86 (0.75–0.97) |
3 | 84 (27.1%) | 0.83 (0.78–0.88) | 11 (25.6%) | 0.91 (0.82–1.00) | 73 (27.3%) | 0.82 (0.76–0.88) |
4 | 83 (26.8%) | 0.78 (0.73–0.83) | 14 (32.6%) | 0.93 (0.87–1.00) | 69 (25.8%) | 0.74 (0.68–0.80) |
5 | 49 (15.8%) | 0.66 (0.57–0.75) | 1 (2.3%) | 1.00 | 48 (18.0%) | 0.62 (0.51–0.73) |
6 | 23 (7.4%) | 0.13 (0.05–0.21) | 0 | – | 23 (8.6%) | 0.13 (0.05–0.21) |
7 | 5 (1.6%) | 0 (mTFR = 475 d)b | 0 | – | 5 (1.9%) | 0 (mTFR = 475 d) |
Total | 0.73 (0.70–0.76) | Total | 0.92 (0.88–0.96) | Total | 0.69 (0.65–0.73) | |
Clustered Neo-Bioscore | All patients | pCR | non-pCR | |||
n = 310 | DFS-3y (CI95%) | n = 43 | DFS-3y (CI95%) | n = 267 | DFS-3y (CI95%) | |
0–3 | 150 | 0.87 (0.83–0.91) | 28 (65.1%) | 0.93 (0.87–0.99) | 122 (45.7%) | 0.86 (0.82–0.90) |
4–5 | 132 | 0.73 (0.68–0.78) | 15 (34.9%) | 0.92 (0.86–0.98) | 117 (43.8%) | 0.70 (0.65–0.75) |
6 | 23 (7.4%) | 0.13 (0.05–0.21) | 0 | – | 23 (8.6%) | 0.13 (0.05–0.21) |
7 | 5 (1.6%) | 0 (mTFR = 475 d) | 0 | – | 5 (1.9%) | 0 (mTFR = 475 d) |