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Table 1 Dose Levels of STARPAC clinical trial

From: A new pragmatic design for dose escalation in phase 1 clinical trials using an adaptive continual reassessment method

Dose level

Gemcitabine

Nab-Paclitaxel

ATRA

D1

80%

800 mg/m2

80%

100 mg/m2

33%

15 mg/m2

D2

80%

800 mg/m2

80%

100 mg/m2

66%

30 mg/m2

D3

80%

800 mg/m2

80%

100 mg/m2

100%

45 mg/m2

D4

100%

1000 mg/m2

80%

100 mg/m2

100%

45 mg/m2

D5

100%

1000 mg/m2

100%

125 mg/m2

100%

45 mg/m2

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BMC Cancer

ISSN: 1471-2407

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