Table 4 Response analysis among patients who received cytotoxic chemotherapy as first-line treatment stratified by TTF-1 status
TTF-1 positive (n = 59) | TTF-1 negative (n = 27) | Total (n = 86) | P value | |
|---|---|---|---|---|
EGFR sensitizing mutation (%) | 2 (3.4) | 0 (0) | 2 (2.3) | 1.000 |
Response, no. (%) | ||||
Objective response rate (CR + PR) | 27 (45.8) | 10 (37.0) | 37 (43.0) | 0.448 |
Disease control rate (CR + PR + SD) | 51 (86.4) | 20 (74.1) | 71 (82.6) | 0.161 |
PFS (months), median (95% CI) | 4.9 (3.9–5.8) | 3.0 (2.8–3.2) | 4.4 (3.7–5.2) | 0.004 |