From: Adjuvant chemoradiation in pancreatic cancer: impact of radiotherapy dose on survival
Variable | Value | No. of patients | 2-year OS (%) | 5-year OS (%) | Median OS (months) | P value |
---|---|---|---|---|---|---|
Gender | Male | 239 | 50.0 | 23.8 | 25 | .084 |
Female | 275 | 43.1 | 18.0 | 21 | ||
Ca 19.9 (units/mL) | < 90 | 114 | 62.6 | 31.5 | 32 | .000 |
≥ 90 | 137 | 39.8 | 18.4 | 21 | ||
Tumor Site | Head | 432 | 47.0 | 20.9 | 23 | .909 |
Body | 26 | 40.4 | 11.8 | 21 | ||
Tail | 36 | 44.3 | 15.8 | 22 | ||
Type of resection | DCP | 315 | 48.1 | 22.9 | 23 | .090 |
DP | 61 | 45.1 | 17.4 | 22 | ||
TP | 21 | 20.8 | 10.4 | 16 | ||
PPP | 117 | 47.0 | 18.0 | 22 | ||
Grading | 1 | 34 | 61.8 | 39.2 | 29 | .004 |
2 | 119 | 51.9 | 19.3 | 25 | ||
3 | 250 | 43.7 | 19.3 | 20 | ||
4 | 45 | 35.1 | 19.3 | 15 | ||
Margins status | R0 | 132 | 59.7 | 25.2 | 29 | .004 |
R1 | 61 | 36.8 | 10.8 | 20 | ||
Tumor diameter (mm) | < 30 | 68 | 57.7 | 15.5 | 28 | .529 |
≥ 30 | 61 | 48.4 | 20.3 | 24 | ||
pT-stage | 1 | 33 | 70.3 | 41.9 | 45 | .002 |
2 | 107 | 54.4 | 26.3 | 28 | ||
3 | 341 | 42.7 | 17.5 | 21 | ||
4 | 33 | 33.3 | 14.5 | 18 | ||
pN-stage | N0 | 205 | 56.6 | 30.3 | 30 | .000 |
N+ | 309 | 39.6 | 14.4 | 20 | ||
Adjuvant CT | No | 308 | 43.1 | 21.1 | 20 | .004 |
Yes | 141 | 53.7 | 18.8 | 26 | ||
RT dose (Gy) | < 45 | 26 | 24.0 | 4.0 | 13 | .004 |
≥ 45 and < 50 | 72 | 44.6 | 25.1 | 21 | ||
≥ 50 and < 55 | 332 | 44.9 | 22.0 | 22 | ||
≥ 55 | 84 | 59.5 | 18.4 | 28 |