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Table 4 Multivariate analysis of prognostic factors

From: Advantages of using reduced-volume intensity modulated radiation therapy for the treatment of nasopharyngeal carcinoma: a retrospective paired study

Variate

OS

PFS

DMFS

LRRFS

RR(95% CI)

P

RR(95% CI)

P

RR(95% CI)

P

RR(95% CI)

P

Group

RV-IMRT vs. CV-IMRT

0.580 (0.257–1.309)

0.19

0.826 (0.420–1.622)

0.578

1.285 (0.538–3.070)

0.573

0.553 (0.203–1.502)

0.245

Gender

 Male vs. Female

0.970 (0.382–2.464)

0.95

1.918 (0.736–4.998)

0.183

2.979 (0.684–12.978)

0.146

1.563 (0.439–5.562)

0.49

Age

  ≥ 45 vs. < 45

2.408 (1.037–5.595)

0.041

1.451 (0.724–2.908)

0.294

1.053 (0.438–2.528)

0.909

1.607 (0.575–4.490)

0.365

T stage

 T3–4 vs. T1–2

0.817 (0.340–1.964)

0.651

0.916 (0.415–2.021)

0.828

1.068 (0.396–2.885)

0.896

1.179 (0.368–3.776)

0.781

N stage

 N2–3 vs. N0–1

2.455 (0.649–9.279)

0.186

2.192 (0.687–6.992)

0.185

2.715 (0.556–13.257)

0.217

1.490 (0.361–6.159)

0.581

Clinical stage

 III-IV vs. I-II

3.280 (0.281–38.226)

0.343

0.926 (0.183–4.683)

0.926

0.730 (0.080–6.639)

0.78

1.165 (0.129–10.480)

0.892

Neoadjuvant/adjuvant chemotherapy

 Yes vs. No

0.600 (0.085–4.238)

0.608

0.695 (0.108–4.464)

0.702

1.764 (0.084–36.960)

0.715

0.404 (0.047–3.457)

0.408

Concurrent chemotherapy

 Yes vs. No

0.987 (0.041–23.701)

0.994

3.338 (0.237–46.915)

0.371

0.796 (0.030–20.935)

0.891

–

–

  1. OS overall survival, PFS progression-free survival, DMFS distant metastasis-free survival, LRRFS locoregional recurrence-free survival, CV-IMRT conventional-volume intensity-modulated radiation therapy, RV-IMRT reduced-volume intensity-modulated radiation therapy