Table 4 Adverse Events
Adverse Event | FP (n = 64) | F (n = 65) | p-value | |||
|---|---|---|---|---|---|---|
All Gr. | Gr. 3–4 | All Gr. | Gr. 3–4 | |||
No. (%) | No. (%) | No. (%) | No. (%) | All Gr. | Gr. 3–4 | |
Leukocytopenia | 40 (63) | 11 (17) | 23 (35) | 5 (8) | < 0.01 | 0.10 |
Neutropenia | 39 (61) | 23 (36) | 17 (26) | 7 (11) | < 0.01 | < 0.01 |
Anemia | 51 (80) | 12 (19) | 37 (57) | 15 (23) | < 0.01 | 0.55 |
Thrombocytopenia | 37 (58) | 3 (5) | 9 (14) | 0 (0) | < 0.01 | 0.08 |
Febrile neutropenia | 3 (5) | 3 (5) | 3 (5) | 3 (5) | 0.98 | 0.98 |
Anorexia | 42 (66) | 10 (16) | 37 (57) | 17 (26) | 0.31 | 0.14 |
Nausea | 40 (63) | 3 (5) | 34 (52) | 1 (2) | 0.24 | 0.30 |
Vomiting | 18 (28) | 1 (2) | 23 (35) | 2 (3) | 0.38 | 0.57 |
Diarrhea | 16 (25) | 3 (5) | 18 (28) | 1 (2) | 0.73 | 0.30 |
Stomatitis | 14 (22) | 1 (2) | 7 (11) | 0 (0) | 0.09 | 0.31 |
Fatigue | 27 (42) | 2 (3) | 27 (42) | 3 (5) | 0.94 | 0.66 |
Sensory neuropathy | 24 (38) | 1 (2) | 0 (0) | 0 (0) | < 0.01 | 0.31 |