Fig. 5

Summary roc curve (SROC) and Summary PLR and NLR for cfDNA test: a. SROC of cfDNA based detection of SNV (ABC): The area under the curve (AUC) was 0.91 (0.88–0.93) indicating an impressive overall accuracy; b. Summary PLR and NLR for cfDNA based detection of SNV (ABC): The PLR and NLR were 10.3 (6.6–16.2) and 0.24 (0.18–0.32), respectively, indicating that the detection of SNV through cfDNA has a highly significant detection rate but exhibits a poor exclusion ability