Fig. 3

Diagnostic odds ratio (DOR), Deek’s funnel plot and Fagan’s Nomogram of cfDNA for SNV (ABC): a. The DOR of SNV was 40 (21–75) indicating high diagnostic performance; b. The p value was 0.70 (> 0.05) which suggests that there was no evidence of publication bias for SNV. c. The post-test probability of positive result was raised from 30 to 80%, which indicates a high diagnosis utility of cfDNA for detection of SNV