Table 1 Description of the vitronectin and nuclei morphometric measurements of control tissues and NB primary tumors
From: Vitronectin as a molecular player of the tumor microenvironment in neuroblastoma
Parameter | Median | Mean | SD | Range | Q3 | ||
|---|---|---|---|---|---|---|---|
Normal control tissues other than liver (n = 12) | |||||||
IPP | Nuclei | Density | 308.10 | 305 | 99.75 | 94.10–477.70 | 355 |
%SA | 7.30 | 7.90 | 3.35 | 4–14 | 8.80 | ||
Inter. VN | %SA | 1.57 | 3.92 | 5.70 | 0.42–17 | 3.67 | |
Terr. VN | %SA | 0.04 | 0.07 | 0.07 | 0–0.20 | 0.15 | |
Densito | VN ratio of pixels | Weak | 0.04 | 1 | 1.50 | 0–4 | 1.75 |
Moderate | 2.25 | 10.95 | 13 | 0.06–35 | 22.90 | ||
Strong | 1 | 2 | 2.60 | 0–9 | 2.95 | ||
H-score | 20.45 | 46.40 | 52.51 | 0.16–163 | 82.50 | ||
Liver samples (n = 5) | |||||||
IPP | Nuclei | Density | 616 | 1846.70 | 2384.30 | 472–6051.70 | 3767.80 |
%SA | 4 | 3.80 | 2.05 | 2–7 | 5.50 | ||
Inter. VN | %SA | 20 | 19 | 11.40 | 3–31 | 29.50 | |
Terr. VN | %SA | 3 | 2.50 | 1.30 | 0.65–4 | 3.50 | |
Densito | VN ratio of pixels | Weak | 2.50 | 2.85 | 2.30 | 0.30–6 | 5.15 |
Moderate | 67 | 64.55 | 8.30 | 50–71 | 69.50 | ||
Strong | 12.75 | 13.50 | 2.70 | 10–17 | 16 | ||
H-score | 175.80 | 172.60 | 11.60 | 152.25–181.35 | 179.55 | ||
Primary tumors (n = 91) | |||||||
IPP | Nuclei | Density | 560 | 1074.25 | 1455.80 | 95–6793 | 739 |
%SA | 11.75 | 11.70 | 6.30 | 0.35–29.70 | 15.50 | ||
Inter. VN | %SA | 9.35 | 12.25 | 10.95 | 0.02–40.97 | 18.20 | |
Terr. VN | %SA | 0.71 | 2.95 | 4.45 | 0.01–20.70 | 4.50 | |
Densito | VN ratio of pixels | Weak | 0.80 | 1.60 | 2.40 | 0.01–14.65 | 2.10 |
Moderate | 35 | 36.10 | 24.70 | 0.05–88.10 | 56.75 | ||
Strong | 3.55 | 12.85 | 17.85 | 0.01–61.85 | 20.40 | ||
H-score | 110.91 | 112.85 | 78.55 | 1.07–257.60 | 183.80 | ||