PD-1 high expression predicts lower local disease control in stage IV M0 nasopharyngeal carcinoma

BMC Cancer

Table 2 Multivariate cox regression analyses estimating the associations of factors with patient survival

Variables	OS		LRFS
Variables	Exp (B) (95.0% CI)	P value	Exp (B) (95.0% CI)	P value
PD-1 expression	3.87 (1.27–11.84)	0.018	16.89 (1.27–11.84)	0.007
High vs low	3.87 (1.27–11.84)	0.018	16.89 (1.27–11.84)	0.007
T stage	1.36 (0.69–2.67)	0.374	4.50 0.66–30.85	0.126
N stage	1.41 (0.81–2.47)	0.224	–	–
Induction chemotherapy	1.53 (0.51–4.56)	0.449	5.89 (0.74–46.68)	0.094
No vs yes	1.53 (0.51–4.56)	0.449	5.89 (0.74–46.68)	0.094
Concurrent chemotherapy No vs yes	1.416 (1.17–12.09)	0.750	2.899 (0.36–23.28)	0.317
Gender	0.69 (0.19–2.57)	0.579	0.85 (0.18–4.03)	0.835
Female vs male	0.69 (0.19–2.57)	0.579	0.85 (0.18–4.03)	0.835
Age	0.68 (0.25–1.88)	0.460	0.70 (0.40–1.25)	0.225
< 47 vs ≥47	0.68 (0.25–1.88)	0.460	0.70 (0.40–1.25)	0.225
Pathology	0.65 (0.08–5.39)	0.692	0.379 (0.08–1.86)	0.232
Non-keratinizing vs keratinizing	0.65 (0.08–5.39)	0.692	0.379 (0.08–1.86)	0.232

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