Fig. 4

Quantification of immunofluorescence staining of γ-H2AX (a) and pimonidazole (b). Images were assessed for percent area stained positive for each marker. Mean percent coverage was determined for each dose group and time point (n = 18 images per group), with error bars indicating standard error on the mean. **** p ≤ 0.0001, *** p ≤ 0.001