Fig. 1

ETS-1 increases in cisplatin resistant HNSCC cells. a. IC₅₀ values to cisplatin in the cisplatin-sensitive and resistant HNSCC cells are listed. Cells were treated with increasing doses of cisplatin for 72 h and IC₅₀ values were determined. b. ETS-1 protein levels were examined in the indicated cells by Western blot analysis. The experiments were repeated for three times. Note: (S) indicates sensitivity to cisplatin and (R) indicates resistance to cisplatin. C. ETS-1 expression levels were examined in cisplatin-sensitive (Patient ID: 784116) and resistant (Patient ID: 871537) PDX by Western blot