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Table 3 Basic characteristics and allele frequencies of the six SNPs in the TIMP-2 gene

From: Association between TIMP-2 gene polymorphism and breast cancer in Han Chinese women

SNP Gene chromosome Position Allele Minor allele frequency HWE p value OR (95%CI) p
Case Control
rs2277698 TIMP-2 17q25.3 76,867,017 T/C 0.201 0.236 0.0651 0.81(0.67–0.99) 0.041*
rs2009196 TIMP-2 17q25.3 76,870,581 C/G 0.392 0.426 0.3502 0.87(0.74–1.03) 0.099
rs7342880 TIMP-2 17q25.3 76,874,512 A/C 0.161 0.150 0.7433 1.09(0.87–1.37) 0.448
rs11654470 TIMP-2 17q25.3 76,877,331 C/T 0.23 0.273 0.0119* 0.80(0.66–0.96) 0.019
rs2003241 TIMP-2 17q25.3 76,885,117 C/T 0.164 0.161 0.0196* 1.02(0.82–1.28) 0.853
rs4789936 TIMP-2 17q25.3 76,897,974 T/C 0.299 0.307 0.6256 0.96(0.80–1.15) 0.658
  1. SNP: single nucleotide polymorphism; OR: odds ratio; 95%CI: 95% confidence interval; HWE: Hardy-Weinberg equilibrium
  2. *p < 0.05 indicates statistical significance