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Table 2 Univariate analysis of survival after recurrence

From: Association of pathway mutation with survival after recurrence in colorectal cancer patients treated with adjuvant fluoropyrimidine and oxaliplatin chemotherapy

Variable

 

Median SAR (months)

p-value

Age

< 65 years

36.7 (26.0–47.3)

0.71

 

≥65 years

45.6 (29.4–61.8)

 

Sex

Male

37.8 (33.6–42.1)

0.49

 

Female

55.4 (0.0–110.8)

 

Location

Proximal

37.8 (13.9–61.8)

0.82

 

Distal

38.7 (27.9–49.4)

 

Time to recurrence

< 1 year

31.7 (5.9–57.6)

0.16

 

≥1 year

44.4 (31.4–57.4)

 

Stage

II, high risk

49.7 (N/A)

0.36

 

III

37.8 (30.2–45.5)

 

T-stage

T1–3

38.2 (29.0–47.4)

0.31

 

T4

28.1 (0.0–64.8)

 

N-stage

N0–1

49.7 (26.1–73.3)

0.064

 

N2

29.3 (11.4–47.3)

 

Histology

Non-MAC

44.4 (31.2–54.7)

0.003

 

MAC

20.0 (4.9–35.0)

 

Curative resection after distant recurrence

Not done

23.6 (12.1–35.2)

< 0.001

Done

Not reached

 

MSI

MSS/MSI-L

38.2 (28.2–48.2)

0.35

 

MSI-H

9.3 (1.7–38.2)

 
  1. Abbreviations: MAC mucinous adenocarcinoma, MSS microsatellite stable, MSI-L microsatellite instability-low, MSI-H microsatellite instability-high, N/A not available