Table 2 Validation cohort clinicopathological details
Clinicopathological details | Metastatic (n = 22) | Local (n = 31) | Healthy Controls (n = 21) |
|---|---|---|---|
Age - mean years (SD) | 60 (±15 years) | 54 (±12 years) | 52 (±12 years) |
Histological Subtype | Ductal (n = 17) Lobular (n = 5) | Ductal (n = 31) | – |
Molecular Subtype | Luminal A (n = 22) | Luminal A (n = 31) | – |
Stage | IV (n = 22) | I (n = 10) II (n = 17) III (n = 4) | – |
Tumour Grade |  | 1 (n = 6) 2 (n = 17) 3 (n = 8) | – |
Nodal Status |  | N positive (n = 11) N negative (n = 20) | – |
Metastasis location | Bone (n = 17) Lung (n = 3) Liver (n = 2) | – | – |
Time Sample Taken | M1 at presentation (n = 14) Metastatic at follow up (n = 8) | Pre-operatively (n = 31) | – |