Table 1 Patient demographics, clinical characteristics and univariate analysis (log rank test) influencing the overall survival (OS) disease free survival (DFS)
N (%) | OS [months] | P | DFS [months] | P | |
|---|---|---|---|---|---|
all | 619 (100) | ||||
age (years) | |||||
< 65 | 303 (48.9) | n.a. | < 0.001 | 59.5 | 0.005 |
≥ 65 | 315 (50.9) | 65.6 | n.a. | ||
unknown | 1 (0.2) | ||||
sex | |||||
male | 312 (50.4) | 119.1 | 0.961 | n.a. | 0.218 |
female | 307 (49.5) | 104.3 | n.a. | ||
tumor site | |||||
right colon | 172 (27.8) | 130.5 | 0.010 | n.a. | 0.299 |
left colon + rectum | 439 (70.1) | 69.5 | n.a. | ||
unknown | 8 (1.3) | ||||
UICC | |||||
I + II | 297 (48.0) | 154.6 | < 0.001 | n.a. | < 0.001 |
III | 199 (32.1) | 87.0 | 49.8 | ||
IV | 117 (18.9) | 22.1 | 13.7 | ||
unknown | 6 (1.0) | ||||
histological grading | |||||
I | 10 (1.6) | n.a. | < 0.001 | n.a. | 0.007 |
II | 505 (81.6) | 122.4 | n.a. | ||
III | 102 (16.5) | 41.8 | 33.6 | ||
unknown | 2 (0.3) | ||||
histology | |||||
adeno carcinoma | 525 (84.9) | 122.6 | < 0.001 | n.a. | 0.010 |
mucinous carcinoma | 74 (12.0) | 68.3 | 40.7 | ||
signet-ring cell carcinoma | 7 (1.1) | 12.3 | 9.4 | ||
unknown | 13 (2.1) | ||||
resection margin | |||||
R0 | 573 (92.6) | 15.3 | < 0.001 | n.a. | < 0.001 |
R1 + R2 | 32 (5.2) | 122.6 | 10.7 | ||
unknown | 14 (2.3) | ||||
therapy | |||||
sole surgical resection | 229 (37.0) | ||||
+ chemotherapy | 136 (22.0) | ||||
+ radiation | 10 (1.6) | ||||
+ chemoradiation | 111 (17.9) | ||||
+ unknown | 133 (21.5) | ||||