Fig. 4From: Ιmpact of sunitinib-induced hypothyroidism on survival of patients with metastatic renal cancerEarly increase in TSH predicted longer OS. Patients with a TSH increase more than twice their baseline value on day-15 exhibited a longer OS than those with a TSH increase less than twice their baseline value (3.1 vs 1.08 years, HR 1.73, 95% CI: 1.556–5.394, p = 0.0011) (Log-Rank test). The result is statistically significantBack to article page