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Table 2 Univariate and multivariate analyses of OS in patients

From: Irreversible electroporation versus radiotherapy after induction chemotherapy on survival in patients with locally advanced pancreatic cancer: a propensity score analysis

Characteristic Before PSM After PSM
Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis
HR 95%CI P HR 95%CI P HR 95% CI P HR 95% CI P
Age (years) ≤60/> 60 1.718 0.880–3.356 0.113    NI 1.443 0.734–2.837 0.288    NI
Gender Female / Male 1.537 0.764–3.093 0.228    NI 1.930 0.953–3.908 0.068    NI
Tumor size (cm) ≤2/2~4/>4 1.158 0.636–2.108 0.631    NI 1.404 0.763–2.584 0.275    NI
Tumor grade Well / Moderate / Poor 1.030 0.597–1.778 0.915    NI 1.188 0.681–2.072 0.545    NI
LN metastasis Absent / Present 0.677 0.332–1.379 0.282    NI 0.787 0.386–1.604 0.509    NI
Tumor site Head / Body / Tail 0.942 0.575–1.544 0.814    NI 1.003 0.598–1.681 0.992    NI
WBC (*109) ≤10/> 10 1.008 0.354–2.872 0.988    NI 0.878 0.305–2.525 0.809    NI
HGB (g/L) ≤120/> 120 0.656 0.254–1.693 0.383    NI 0.445 0.169–1.174 0.102    NI
PLT (*109) ≤300/> 300 1.220 0.503–2.957 0.660    NI 1.521 0.614–3.764 0.365    NI
ALT (U/L) ≤40/>40 0.768 0.348–1.696 0.514    NI 0.790 0.356–1.752 0.562    NI
AST (U/L) ≤40/>40 0.497 0.175–1.410 0.189    NI 0.540 0.190–1.537 0.248    NI
ALP (U/L) ≤100/>100 0.919 0.456–1.854 0.813    NI 0.905 0.446–1.840 0.784    NI
GGT (U/L) ≤45/>45 0.898 0.459–1.760 0.755    NI 0.989 0.501–1.950 0.974    NI
ALB (g/L) ≤40/> 40 0.317 0.117–0.857 0.024 0.363 0.130–1.012 0.053 0.346 0.128–0.934 0.036 0.389 0.141–1.076 0.069
TBIL (umol/L) ≤20.5/>20.5 0.649 0.251–1.675 0.371    NI 0.715 0.275–1.855 0.490    NI
IBIL (umol/L) ≤15/>15 0.483 0.066–3.557 0.475    NI 0.437 0.059–3.215 0.416    NI
CRP (ng/L) ≤3/>3 4.040 1.974–8.266 <0.001 3.567 1.741–7.309 0.001 3.939 1.867–8.311 <0.001 3.432 1.628–7.238 0.001
CEA (ng/mL) ≤5/>5 1.372 0.687–2.741 0.370    NI 1.414 0.702–2.850 0.333    NI
CA19–9 (U/ml) ≤35/>35 1.650 0.720–3.782 0.237    NI 2.056 0.848–4.987 0.111    NI
Chemotherapy With IRE/ With radiotherapy 0.424 0.183–0.892 0.045 0.422 0.177–0.998 0.049 0.355 0.154–0.822 0.016 0.362 0.153–0.854 0.020
Cheotherapy type FOLFIRINOX/Gem 0.834 0.596–1.168 0.291    NI 0.864 0.613–1.219 0.407    NI
  1. Abbreviations as in Table 1