Fig. 5

The role of hepatic cells and HSCs in the malignant progression of HCC. HSCs induce secretion of CCN3, which in turn inhibits proliferation of HSCs. HSCs and activated hepatic cells exert paracrine effects to promote HCC progression
The role of hepatic cells and HSCs in the malignant progression of HCC. HSCs induce secretion of CCN3, which in turn inhibits proliferation of HSCs. HSCs and activated hepatic cells exert paracrine effects to promote HCC progression