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Fig. 1 | BMC Cancer

Fig. 1

From: Paracrine effects of CCN3 from non-cancerous hepatic cells increase signaling and progression of hepatocellular carcinoma

Fig. 1

CCN3 expression in non-cancerous hepatic tissues correlates with metastasis and poor prognosis in HCC patients. CCN3 is significantly upregulated in non-cancerous hepatic tissues from patients with metastatic HCC based on cDNA microarray-based gene expression profiling (a). CCN3 mRNA levels are upregulated in patients with metastatic HCC (b). CCN3 staining localizes primarily to the cytoplasm of hepatic cells (c). Patients with high expression of CCN3 exhibit significantly lower OS and higher TRR (d)

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