Fig. 1
From: Salinomycin triggers endoplasmic reticulum stress through ATP2A3 upregulation in PC-3 cells
Gene expression changes induced by salinomycin in vitro and in vivo. a. Log–log scatter-plot of the microarray results. Plots in region Y represent upregulated genes, while plots in region X represent downregulated genes. b. Venn diagram displaying the number of DEGs. c. Heatmap representation of genes whose expression is differently regulated by salinomycin in vitro and in vivo. d. Chart showing the enriched gene ontology (GO) terms in the category of biological processes for DEGs. e. Chart showing the enriched gene ontology (GO) terms in the category of molecular functions for DEGs. f. Validation of the expression of DEGs by quantitative RT-PCR. The expression levels of mRNA were analyzed using delta cycle threshold (ΔCt) values