| |
Primary(N = 83)
|
Metastasis (N = 163)a
|
|---|
|
n(%)
|
Lung/lymph node n = 72
|
Bone n = 41
|
Brain n = 19
|
Viscera n = 16
|
Adrenal gland n = 6
|
Others n = 20
|
Total n(%)
|
|---|
|
PD-1
|
|
Negative
|
57(68.7)
|
25(34.7)
|
28(68.3)
|
17(89.5)
|
14(87.5)
|
5(83.3)
|
12(60.0)
|
101(58.0)
|
|
Positive
|
26(31.3)
|
47(65.3)
|
13(31.7)
|
2(10.5)
|
2(12.5)
|
1(16.7)
|
8(40.0)
|
73(42.0)
|
|
P value
| |
< 0.001
|
0.77
|
< 0.001
|
0.01
|
0.21
|
0.85
|
0.11
|
|
PD-L1
|
|
Negative
|
63(75.9)
|
45(62.5)
|
36(87.8)
|
13(68.4)
|
11(68.8)
|
5(83.3)
|
14(70.0)
|
124(71.3)
|
|
Positive
|
20(24.1)
|
27(37.5)
|
5(12.2)
|
6(31.6)
|
5(31.3)
|
1(16.7)
|
6(30.0)
|
50(28.7)
|
|
P value
| |
0.03
|
0.01
|
0.77
| |
0.51
|
0.89
|
0.44
|
|
PD-L2
|
|
Negative
|
69(83.1)
|
55(76.4)
|
31(75.6)
|
17(89.5)
|
10(62.5)
|
3(50.0)
|
17(85.0)
|
133(76.4)
|
|
Positive
|
14(16.9)
|
17(23.6)
|
10(24.4)
|
2(10.5)
|
6(37.5)
|
3(50.0)
|
3(15.0)
|
41(23.6)
|
|
P value
| |
0.99
|
0.21
|
0.16
|
0.17
|
0.12
|
0.34
|
0.22
|
- a11 cases have two metastatic sites
