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Table 2 Differential expressions of PD-1,PD-L1 and PD-L2 between the primary and metastatic tumors

From: Differential expressions of PD-1, PD-L1 and PD-L2 between primary and metastatic sites in renal cell carcinoma

  Primary(N = 83) Metastasis (N = 163)a
n(%) Lung/lymph node n = 72 Bone n = 41 Brain n = 19 Viscera n = 16 Adrenal gland n = 6 Others n = 20 Total n(%)
PD-1
 Negative 57(68.7) 25(34.7) 28(68.3) 17(89.5) 14(87.5) 5(83.3) 12(60.0) 101(58.0)
 Positive 26(31.3) 47(65.3) 13(31.7) 2(10.5) 2(12.5) 1(16.7) 8(40.0) 73(42.0)
P value   < 0.001 0.77 < 0.001 0.01 0.21 0.85 0.11
PD-L1
 Negative 63(75.9) 45(62.5) 36(87.8) 13(68.4) 11(68.8) 5(83.3) 14(70.0) 124(71.3)
 Positive 20(24.1) 27(37.5) 5(12.2) 6(31.6) 5(31.3) 1(16.7) 6(30.0) 50(28.7)
P value   0.03 0.01 0.77   0.51 0.89 0.44
PD-L2
 Negative 69(83.1) 55(76.4) 31(75.6) 17(89.5) 10(62.5) 3(50.0) 17(85.0) 133(76.4)
 Positive 14(16.9) 17(23.6) 10(24.4) 2(10.5) 6(37.5) 3(50.0) 3(15.0) 41(23.6)
P value   0.99 0.21 0.16 0.17 0.12 0.34 0.22
  1. a11 cases have two metastatic sites
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