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Table 1 Clinical and pathologic characteristics of the patients included in the study. All p values were based on 2-tailed chi square test

From: A preliminary investigation of circulating extracellular vesicles and biomarker discovery associated with treatment response in head and neck squamous cell carcinoma

Variables N of cases (%) CR n (%) NR n (%) X2 (p value)
Gender Male 12 (100.0) 6 (50.0) 6 (50.0) 1.0
Female 0 (0) 0 (0) 0 (0)
Age <=60 years 10 (83.3) 5 (41.7) 5 (41.7) 1.0
> 60 years 2 (16.7) 1 (8.3) 1 (8.3)
Tobacco Consumption yes 11 (91.7) 6 (50.0) 5 (41.7) 0.2963
no 1 (8.3) 0 (0) 1 (8.3)
Tumor site Oral Cavity 2 (16.7) 0 (0.0) 2 (16.7) 0.6283
Oropharynx 8 (66.7) 4 (33.3) 4 (33.3)
Larynx 2 (16.7) 2 (16.7) 0 (0.0)
HPV statusa p16+ 1 (8.33) 1 (8.3) 0 (0.0) 0.2963
p16- 11 (81.7) 5 (41.7) 6 (50.0)
Tumor stage III 3 (25.0) 3 (25.0) 0 (0) 0.1824
IV 9 (75.0) 3 (25.0) 6 (50.0)
  1. Abbreviations: CR complete response to chemoradiotherapy, NR incomplete response to chemoradiotherapy
  2. aHPV status was determined retrospectively using archival tumor specimens