Fig. 2
From: Intratumor heterogeneity index of breast carcinomas based on DNA methylation profiles
Heterogeneity index of cancer cell lines inferred from methylation profile obtained by MS-MLPA. a. Heat map showing the methylation status of 60 CpG sites (in columns) on 5 cancer cell lines (K-562, HeLa, MCF7, T47D and MDA-MB 231), represented in rows. A color gradient from blue-white-red is used to represent low to high values of methylation (from 0 to 1). b. HI calculated for the 5 cancer cell lines represented in box plot graph. The HIs are statistically different as assed by ANOVA with Tukey post hoc test p < 0.0001