Differential proteomic comparison of breast cancer secretome using a quantitative paired analysis workflow

BMC Cancer

Table 2 Theoretical example for the peptide-centric approach in the PA module of the PatternLab tool

Peptide^a	1^b	2	3	4	5	6	7	8	9	10	p-value^c	Avg Log Fold^d
Pa	0	+	0	0	0	0.19	0.86	1.37	1.63	0	0.50	−0.36
Pb	0.68	1.15	0.30	0.23	+	–	0.18	0.10	0.57	0.42	0.99	−1.53
Pc	0	3.64	+	1.06	+	0	+	0	8.31	0	0.02	1.67

^aThe first column refers to three distinct peptides (Pa, Pb, and Pc)
^bColumns labeled as 1 through 10 refer to distinct patients
^cThe column labeled as p-value refers to the p-value as obtained from the binomial distribution
^dThe Avg Log Fold column displays the average logarithm to the base 2 of the values in the corresponding row that are greater than 0

ISSN: 1471-2407