From: Changes of N6-methyladenosine modulators promote breast cancer progression
Parameter | Status (No.) | METTL3 (mRNA) | METTL14 (mRNA) | WTAP (mRNA) | KIAA1429 (mRNA) | FTO (mRNA) | ALKBH5 (mRNA) |
---|---|---|---|---|---|---|---|
Age | ≤51 (16) | 0.89 ± 0.54 | 0.80 ± 0.53 | 0.80 ± 0.44 | 2.14 ± 1.31 | 0.92 ± 1.71 | 1.59 ± 1.23 |
> 51 (20) | 0.72 ± 0.50 | 0.81 ± 0.56 | 0.79 ± 0.36 | 1.85 ± 1.24 | 0.76 ± 0.46 | 1.78 ± 1.38 | |
ER (IHC) | - (13) | 0.55 ± 0.18 | 0.53 ± 0.30 | 0.81 ± 0.41 | 1.44 ± 1.39 | 0.59 ± 0.63 | 1.07 ± 0.50 |
+(23) | 0.89 ± 0.59* | 0.93 ± 0.59* | 0.78 ± 0.38 | 2.21 ± 1.12 | 0.92 ± 0.49* | 2.02 ± 1.48* | |
PR (IHC) | -(15) | 0.59 ± 0.23 | 0.65 ± 0.36 | 0.78 ± 0.44 | 1.33 ± 0.90 | 0.63 ± 0.46 | 1.08 ± 0.23 |
+(21) | 0.95 ± 0.63* | 0.96 ± 0.64* | 0.81 ± 0.35 | 2.33 ± 1.07* | 1.01 ± 0.58* | 2.20 ± 1.52* | |
HER2 (IHC) | -(14) | 0.72 ± 0.38 | 0.81 ± 0.45 | 0.77 ± 0.36 | 2.46 ± 1.32 | 0.74 ± 0.41 | 1.48 ± 0.71 |
+(22) | 0.81 ± 0.58 | 0.81 ± 0.59 | 0.80 ± 0.40 | 1.67 ± 1.11 | 0.86 ± 0.62 | 1.83 ± 1.55 | |
TNBC | +(4) | 0.31 ± 0.07 | 0.30 ± 0.21 | 0.60 ± 0.09 | 0.89 ± 0.36 | 0.41 ± 0.33 | 1.13 ± 0.68 |
-(32) | 0.83 ± 0.51* | 0.96 ± 0.54 | 0.81 ± 0.40 | 2.08 ± 1.26 | 0.86 ± 0.56 | 1.77 ± 1.36 |