Fig. 3

HPV-HPV junction resulted in HPV deletions in the HPV genome. The examples of 3 tumors (683, 711, 601) with different HPV copy number showed two different HPV populations, and the deleted HPV population resulted from HPV-HPV junctions within them. The exact nucleotide positions for the HPV-HPV junctions in the HPV16 genome and the junction sequence reads are listed below. We also represented the map of the potential full HPV and deleted partial HPV genome for each tumor