Table 1 Percentages of the different immune cells of viable peripheral blood mononuclear cells in patients with classical Hodgkin lymphoma (cHL), high-grade B-cell lymphoma (HGBCL) and healthy blood donors. Mann-Whitney U test was performed comparing the different groups and p-values refer to all lymphoma patients vs healthy blood donors

T-cells CD3+

41.8/45.1 (3.9–65) 15.6

40.2/37.9 (14.8–61.4) 11.8

50.7/53.4 (36–64.1) 9.5

T-regulatory cells

CD3⁺/CD4⁺/CD25⁺/CD127^low

4.4/3.8 (0.4–10.9) 2.4

5.3/4 (1.2–30.5) 5.9

4.1/3.4 (0.4–8) 2.5

CD4+/CD8+ ratio

2/1.6 (0.18–4.9) 1.4

2.9/1.9 (0.5–16.2) 3.4

2/1.6 (0.53–7.4)

Monocytes CD33⁺⁺/CD14⁺/HLA-DR⁺

20.9/20.6 (4–47) 11.7

25.2/22.8 (9.3–66) 11.8

18.7/18.5 (3.5–33) 8.8

NK cells CD7⁺/CD3⁻CD56⁺/CD16⁺

6.5/4.4 (0.29–27.6) 6.1

6.4/5.2 (0.2–24.8) 5.5

9/8.9 (0.04–19.4) 4.9

NK regulatory cells CD7⁺/CD3⁻/CD56⁺⁺/CD16^dim/−

0.28/0.21 (0.007–0.89) 0.26

0.31/0.25 (0.003–0.92) 0.25

0.54/0.44 (0.02–1.6) 0.36

Monocytic MDSC

CD11b⁺/HLA-DR⁻/CD33⁺/CD14⁺

1.1/0.53 (0.043–3.7) 1.1

0.61/0.41 (0.024–2.2) 0.57

0.49/0.31 (0.015–2.7) 0.66

Granulocytic MDSC

CD11b⁺/HLA-DR^dim/CD33^dim/CD14-

12.7/8.1 (0.6–83.8) 18.3

5.7/4.2 (0.4–19.3) 4.96

3.8/1.1 (0.18–17.4) 5.2