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Table 2 Analysis of the factors influencing the postoperative prognosis of patients with giant cell tumor of the extremities

From: The prognostic significance of the neutrophil-to-lymphocyte ratio and the platelet-to-lymphocyte ratio in giant cell tumor of the extremities

clinical parameters

total

Number of recurrence

Univariate analysis

multivariate analysis

HR (95% CI)

p-value

Adjusted HR (95% CI)

p-value

age (year)

38.49 ± 11.10

30

1.00 (0.96~1.03)

0.769

0.99 (0.95~1.03)

0.541

sex

 Male

91

19

1.00

 

1.00

 

 Female

72

11

0.68 (0.32~1.42)

0.302

0.86 (0.39~1.93)

0.717

Companacci stage

 I-II stage

86

6

1.00

 

1.00

 

 III stage

77

24

5.95 (2.42~14.63)

< 0.001

3.28 (1.24~8.69)

0.017

surgical method

 expanded curettage

94

17

1.00

   

 extensive resection

69

13

1.15 (0.56~2.37)

0.708

  

tumor diameter (cm)

5 (4~7)

30

1.12 (0.93~1.36)

0.234

  

ALP(U/L)

79 (63~122)

30

1.01 (1.00~1.01)

0.026

1.00 (0.99~1.00)

0.284

white blood cell (109/L)

6.03 (5.12~7.06)

30

1.08 (0.84~1.39)

0.539

  

ESR (mm/h)

17 (9~34)

30

1.01 (0.99~1.03)

0.232

  

CRP (mg/L)

8.16 (3.77~13.57)

30

1.02 (1.01~1.03)

0.004

1.02 (0.99~1.04)

0.199

NLR

 LNLR

113

10

1.00

 

1.00

 

 HNLR

50

20

5.90 (2.75~12.67)

< 0.001

4.18 (1.83~9.57)

0.001

PLR

 LPLR

90

9

1.00

 

1.00

 

 HPLR

73

21

3.17 (1.45~6.92)

0.004

2.15 (0.90~5.14)

0.084

  1. HR, hazard ratio; CI, confidence interval; ALP, alkaline phosphatase; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; LNLR, low NLR; HNLR, high NLR; LPLR, low PLR; HPLR, high PLR