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Fig 4 | BMC Cancer

Fig 4

From: Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without increasing cell invasion ability

Fig 4

TSA induces EMT-associated marker expression in NPC cells in a concentration-dependent manner. CNE2 and C666–1 cells were treated with various concentrations of TSA for short period within 48 h, and then cells were harvested and subjected to real-time PCR a and western blot b analysis of EMT-associated E-cadherin, Vimentin, Snail1 and Twist1 gene and protein expressions. *P < 0.05 vs. TSA 0 ng/ml; **P < 0.01 vs. TSA 0 ng/ml; ***P < 0.001 vs. TSA 0 ng/ml; #P < 0.05 vs. TSA 0 ng/ml; ##P < 0.01 vs. TSA 0 ng/ml

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