Table 4 Correlation between Cyclin D1 immunoreactivity and clinico-pathological data
Paramater | Cyclin D1 (Immunolabeling ratio≧ 15.7%) | p | |||
|---|---|---|---|---|---|
Immunolabeling below threshold | Immunolabeling above threshold | ||||
Tumor size (mm) | |||||
 <40 | 15 | 14.70% | 68 | 66.70% | 0.59 |
 ≧40 | 3 | 2.90% | 16 | 15.70% | |
Extra-thyroidal extension | |||||
 Present | 3 | 2.90% | 54 | 52.90% | 0.0002* |
 Absent | 15 | 14.70% | 30 | 29.40% | |
Intraglandular metastasis | |||||
 Present | 0 | 0.00% | 26 | 25.50% | 0.0006* |
 Absent | 18 | 17.70% | 58 | 56.90% | |
Lymph node metastasis | |||||
 Positive | 1 | 1.00% | 49 | 48.00% | <.0001* |
 Negative | 17 | 16.70% | 35 | 34.30% | |
Distant metastasis | |||||
 Present | 4 | 3.90% | 24 | 23.50% | 0.6 |
 Absent | 14 | 13.70% | 60 | 58.80% | |