Table 5 Risk of bias within the external validation studies by models
From: Prognostic models for breast cancer: a systematic review
No | Model | Validated by | Authors(Year of publication) | Risk of bias domain | |||
|---|---|---|---|---|---|---|---|
Study Participation | Prognostic Factor Measurement | Outcome Measurement | Statistical Analysis and Presentation | ||||
1 | Adjuvant! | Model developer(s) | Mook et al. (2009) [64] | Low | Moderate | Moderate | Low |
Olivotto et al. (2005) [45] | Low | High | Low | Low | |||
Wishart et al. (2011) [46] | Low | High | Low | Low | |||
Wishart et al. (2012) [35] | Low | High | Low | Low | |||
Independent researcher(s) | Campbell et al. (2009) [59] | Low | Moderate | Low | Low | ||
Hajage et al. (2011) [58] | Moderate | Low | Moderate | Low | |||
Hearne et al. (2015) [47] | Low | Low | Low | Low | |||
M. Jung et al. (2013) [44] | Low | Moderate | Moderate | Low | |||
Laas et al. (2015) [68] | Moderate | Moderate | Moderate | Low | |||
Lende et al. (2010) [136] | Low | Moderate | Low | Low | |||
Plakhins et al. (2013) [63] | Moderate | Moderate | Low | Low | |||
Quintyne et al. (2013) [60] | Low | Moderate | Moderate | Low | |||
Rejali et al. (2015) [54] | Moderate | Moderate | Moderate | Low | |||
de Glas et al. (2014) [66] | Low | Moderate | Low | Low | |||
Bhoo-Pathy et al. (2012) [61] | Low | Moderate | Moderate | Low | |||
Kuo et al. (2012) [62] | Low | Low | Moderate | Low | |||
Mojir Sheibani et al. (2013) [65] | Low | Low | Moderate | Low | |||
2 | NPI | Model developer(s) | van Belle et al. (2010a) [73] | Low | Moderate | Low | Low |
Independent researcher(s) | Albergaria et al. (2011) [75] | Moderate | Moderate | Low | Low | ||
Balslev et al. (1994) [48] | Low | High | Low | Low | |||
Chollet et al. (2003) [49] | Moderate | High | Low | Low | |||
D’Eredita et al. (2001) [51] | Low | Low | Low | Low | |||
Hearne et al. (2015) [47] | Low | Low | Low | Low | |||
M. Liu et al. (2010) [74] | Low | Moderate | Low | Low | |||
Megha et al. (2010) [70] | Moderate | Moderate | Low | Low | |||
Okugawa et al. (2009) [52] | Low | Low | Low | Low | |||
Quintyne et al. (2013) [60] | Low | Moderate | Moderate | Low | |||
Rejali et al. (2015) [54] | Moderate | Moderate | Moderate | Low | |||
Sidoni et al. (2004) [71] | Moderate | Low | Low | Low | |||
Sundquist et al. (1999) [72] | Low | Moderate | Low | Low | |||
van Belle et al. (2010b) [37] | Low | High | Low | Low | |||
Yadav et al. (2015) [50] | Moderate | Moderate | Low | High | |||
3 | PREDICT v1.3 | Model developer(s) | Wishart et al. (2014) [36] | Low | Moderate | Low | Low |
Independent researcher(s) | de Glas et al. (2016) [69] | Low | Moderate | Low | Low | ||
Laas et al. (2015) [68] | Moderate | Moderate | Moderate | Low | |||
Plakhins et al. (2013) [63] | Moderate | Moderate | Low | Low | |||
Wong et al. (2015) [67] | Low | Moderate | Low | Low | |||
4 | Cancer Math | Model developer(s) | Michaelson et al. (2011) [42] | Low | High | Low | Moderate |
Independent researcher(s) | Laas et al. (2015) [68] | Moderate | Moderate | Moderate | Low | ||
Miao et al. (2016) [138] | Moderate | High | Low | Low | |||
5 | MPI | Independent researcher(s) | Aaltomaa et al. (1983) [130] | Low | Low | Low | Low |
Carbone et al. (1999) [132] | Moderate | Low | Low | Low | |||
Collan et al. (1998) [98] | Moderate | Low | Low | Low | |||
6 | IBTR!2.0 | Model developer(s) | Sanghani et al. (2010) [38] | Moderate | Moderate | Moderate | Low |
Independent researcher(s) | S.P. Jung et al. (2013) [134] | Low | Moderate | Low | Low | ||
Kindts et al. (2016) [135] | Moderate | Moderate | Moderate | Low | |||
7 | Paik et al. (1990) | Independent researcher(s) | Ribelles et al. (1997) [139] | Moderate | Low | Low | Low |
8 | Lovekin et al. (1991) | Independent researcher(s) | Ribelles et al. (1997) [139] | Moderate | Low | Low | Low |
9 | PREDICT v1.1 | Model developer(s) | Wishart et al. (2010b) [40] | Low | High | Low | Low |
Wishart et al. (2011) [46] | Low | High | Low | Low | |||
Wishart et al. (2012) [35] | Low | High | Low | Low | |||
10 | PREDICT v1.2 | Model developer(s) | Maishman et al. (2015) [137] | Moderate | Moderate | Low | Low |
Wishart et al. (2014) [36] | Low | Moderate | Low | Low | |||
Wishart et al. (2012) [35] | Low | High | Low | Low | |||
11 | iNPI | Model developer(s) | van Belle et al. (2010a) [73] | Low | Moderate | Low | Low |
12 | NPI+ | Model developer(s) | Green et al. (2016) [133] | Low | Moderate | Low | Low |
13 | INFLUENCE | Model developer(s) | Witteveen et al. (2015) [39] | Low | Moderate | High | Low |
14 | OPTIONS | Model developer(s) | Campbell et al. (2010) [19] | Moderate | Low | Moderate | Moderate |
15 | Chen et al. (2016) | Model developer(s) | Chen et al. (2016) [41] | Low | High | Low | Low |
16 | de Laurentiis et al. (1999) | Model developer(s) | de Laurentiis et al. (1999) [43] | Moderate | Low | Moderate | Moderate |
17 | Bryan et al. (1986) | Model developer(s) | Alexander et al. (1987) [131] | Low | Low | Low | Low |