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Table 3 Recurrence pattern of patients with early-stage disease at first diagnosis (n = 13)

From: 18F-FDG PET/CT-based metabolic metrics in recurrent tumors of ovarian clear cell carcinoma and their prognostic implications

No

Age

Stage

PFS (Months)

Platinum response

CA125 (U/mL)

Relapsed tumor

SUVmax

Second-line treatment

Status at last follow-up

PRS (Months)

OS (Months)

1

51

II

24

Sensitive

52.56

Vaginal cuff

(−)a

SCS + Chemo

Alive

126

150

2

47

I

48

Sensitive

3.90

Vaginal cuff

(−)a

SCS + Chemo

Alive

94

142

3

53

II

13

Sensitive

10.50

Pelvic tumor

7.2

SCS + Chemo

Dead

29

42

4

54

I

19

Sensitive

4.9

Lung

3.4

SCS + Chemo

Alive

95

114

5

54

I

31

Sensitive

48.60

Multiple lymph nodes

4.7

SCS + Chemo

Dead

43

74

6

53

II

6

Resistant

11.24

Abdominal wall tumor, liver, rectal tumor

13.4

SCS + Chemo

Dead

6

12

7

59

I

20

Sensitive

21.63

Multiple lymph nodes

7.9

SCS + Chemo

Dead

10

30

8

60

I

108

Sensitive

115.30

Supra-diaphragmatic lymph node, Intestinal mesentery, pelvic tumor, vaginal cuff

14.3

SCS + Chemo

Alive

36

144

9

36

I

34

Sensitive

8.31

Spleen

5.4

SCS + Chemo

Dead

24

58

10

46

I

9

Resistant

23.74

Abdominal wall tumor

9.0

SCS + Chemo

Alive

18

27

11

62

I

6

Resistant

40.65

Pelvic tumor

4.9

SCS + Chemo

Alive

13

19

12

34

II

34

Sensitive

154.30

Multiple lymph nodes, peritoneum, liver

20.6

Chemo

Alive

15

49

13

48

I

13

Sensitive

32.21

Pelvic tumor

5.0

SCS

Unknownb

Unknownb

Unknownb

  1. aTwo patients presented with low glucose-uptake tumor
  2. bThis patient lost follow up after second cytoreduction surgery in our hospital
  3. Abbreviations: PFS Progression Free Survival, SUVmax Maximum Standardized Uptake Value, PRS Post-Relapse Survival, OS Overall Survival, SCS Secondary Cytoreduction Surgery, Chemo Chemotherapy