Competing risk analyses of overall survival and cancer-specific survival in patients with combined hepatocellular cholangiocarcinoma after surgery

Table 3 Univariate and multivariate analyses of survival in patients with CHCC after surgery

Characteristic		Overall survival						Cancer-specific survival
		Univariate analysis			Multivariate analysis			Univariate analysis			Multivariate analysis
		HR	95%CI	P	HR	95%CI	P	HR	95%CI	P	HR	95%CI	P
Age (years)	< 60/≥ 60	1.509	1.080–2.109	0.016	1.031	1.006–1.056	0.015	1.674	1.156–2.424	0.006	1.308	1.010–1.067	0.008
Gender	Male/Female	0.942	0.660–1.346	0.745			NI	1.079	0.734–1.585	0.700			NI
Tumor site	Intrahepatic biliary tract/Liver	3.058	1.131–8.267	0.028	2.081	0.650–6.660	0.217	2.575	0.949–6.981	0.063			NI
Tumor grade	Well/Moderate/Poor	1.738	1.177–2.564	0.005	2.049	1.277–3.288	0.003	1.788	1.155–2.765	0.009	2.027	1.195–3.439	0.009
Tumor size	< 5 cm/≥ 5 cm	1.531	1.010–2.320	0.045	1.337	0.791–2.262	0.278	1.912	1.202–3.043	0.006	1.849	1.001–3.427	0.049
T stage (8th)	T1/T2/T3/T4	1.398	1.130–1.729	0.002	1.410	1.071–1.855	0.014	1.505	1.188–1.905	0.001	1.429	1.038–1.969	0.029
LN metastasis	Absent/Present	1.351	0.800–2.282	0.261			NI	1.192	0.653–2.173	0.568			NI

CHCC combined hepatocellular cholangiocarcinoma, LN lymph node, HR hazard ratio, CI confidence interval, NI not included

ISSN: 1471-2407