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Table 3 Univariate and multivariate analyses of survival in patients with CHCC after surgery

From: Competing risk analyses of overall survival and cancer-specific survival in patients with combined hepatocellular cholangiocarcinoma after surgery

Characteristic Overall survival Cancer-specific survival
Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis
HR 95%CI P HR 95%CI P HR 95%CI P HR 95%CI P
Age (years) <  60/≥ 60 1.509 1.080–2.109 0.016 1.031 1.006–1.056 0.015 1.674 1.156–2.424 0.006 1.308 1.010–1.067 0.008
Gender Male/Female 0.942 0.660–1.346 0.745    NI 1.079 0.734–1.585 0.700    NI
Tumor site Intrahepatic biliary tract/Liver 3.058 1.131–8.267 0.028 2.081 0.650–6.660 0.217 2.575 0.949–6.981 0.063    NI
Tumor grade Well/Moderate/Poor 1.738 1.177–2.564 0.005 2.049 1.277–3.288 0.003 1.788 1.155–2.765 0.009 2.027 1.195–3.439 0.009
Tumor size <  5 cm/≥ 5 cm 1.531 1.010–2.320 0.045 1.337 0.791–2.262 0.278 1.912 1.202–3.043 0.006 1.849 1.001–3.427 0.049
T stage (8th) T1/T2/T3/T4 1.398 1.130–1.729 0.002 1.410 1.071–1.855 0.014 1.505 1.188–1.905 0.001 1.429 1.038–1.969 0.029
LN metastasis Absent/Present 1.351 0.800–2.282 0.261    NI 1.192 0.653–2.173 0.568    NI
  1. CHCC combined hepatocellular cholangiocarcinoma, LN lymph node, HR hazard ratio, CI confidence interval, NI not included