|
Characteristic
|
Patients
|
Overall survival rate (%)
|
P
|
Cancer-specific mortality (%)
|
P
|
Non-cancer-specific mortality (%)
|
P
|
|---|
|
No.
|
%
|
1-year
|
2-year
|
3-year
| |
1-year
|
2-year
|
3-year
| |
1-year
|
2-year
|
3-year
| |
|---|
|
Total
| |
230
|
100
|
67.7
|
46.8
|
37.9
| |
25.9
|
45.2
|
53.4
| |
5.9
|
8.0
|
8.0
| |
|
Age (years)
|
≤ 60
|
115
|
50
|
71.8
|
50.2
|
46.9
|
0.014
|
21.1
|
40.8
|
44.2
|
0.007
|
6.4
|
8.5
|
8.5
|
0.442
|
|
> 60
|
115
|
50
|
63.5
|
42.8
|
28.4
|
30.8
|
49.9
|
63.2
|
5.5
|
7.6
|
7.6
|
|
Gender
|
Male
|
161
|
70
|
64.5
|
44.4
|
39.3
|
0.742
|
27.2
|
45.2
|
50.4
|
0.389
|
7.9
|
10.1
|
10.1
|
0.051
|
|
Female
|
69
|
30
|
74.9
|
51.5
|
35.3
|
22.9
|
45.3
|
60.0
|
1.5
|
3.3
|
3.3
|
|
Tumor site
|
Intrahepatic biliary tract
|
16
|
7
|
93.3
|
77.5
|
77.5
|
0.019
|
6.7
|
22.5
|
22.5
|
0.073
|
0
|
0
|
0
|
0.222
|
|
Liver
|
214
|
93
|
65.8
|
44.4
|
35.5
|
27.4
|
46.8
|
55.2
|
6.4
|
8.6
|
8.6
|
|
Tumor grade
|
Well
|
8
|
3
|
80.0
|
80.0
|
60.0
|
0.016
|
20.0
|
20.0
|
40.0
|
0.055
|
0
|
0
|
0
|
0.720
|
|
Moderate
|
92
|
40
|
76.4
|
55.1
|
50.7
|
17.1
|
36.2
|
40.6
|
6.5
|
8.7
|
8.7
|
|
Poor
|
130
|
57
|
59.4
|
35.5
|
23.7
|
31.0
|
53.2
|
63.6
|
8.5
|
11.5
|
11.5
|
|
Tumor size
|
≤ 5 cm
|
137
|
60
|
74.8
|
55.4
|
51.2
|
0.041
|
16.0
|
33.1
|
37.4
|
0.003
|
8.4
|
10.9
|
10.9
|
0.104
|
|
> 5 cm
|
93
|
40
|
65.9
|
43.6
|
30.3
|
30.4
|
51.8
|
63.3
|
3.1
|
4.9
|
4.9
|
|
T stage (8th)
|
I
|
93
|
40
|
82.4
|
62.3
|
55.7
|
0.015
|
11.3
|
29.9
|
34.3
|
0.005
|
6.6
|
8.5
|
8.5
|
0.568
|
|
II
|
83
|
36
|
69.5
|
46.2
|
39.6
|
44.5
|
42.4
|
46.7
|
6.8
|
10.6
|
10.6
|
|
III
|
38
|
17
|
55.2
|
45.8
|
23.8
|
37.7
|
47.0
|
69.1
|
7.1
|
7.1
|
7.1
|
|
IV
|
16
|
7
|
57.1
|
22.9
|
11.4
|
37.7
|
75.1
|
75.1
|
0
|
0
|
0
|
|
LN metastasis
|
Absent
|
204
|
89
|
70.1
|
48.4
|
39.6
|
0.253
|
24.2
|
44.9
|
53.1
|
0.887
|
5.5
|
6.7
|
6.7
|
0.142
|
|
Present
|
26
|
11
|
52.0
|
40.4
|
27.0
|
36.0
|
41.8
|
48.5
|
12.0
|
17.8
|
17.8
|
|
TNM stage (8th)
|
I
|
79
|
34
|
81.5
|
62.7
|
55.4
|
0.014
|
11.3
|
32.5
|
37.4
|
0.084
|
5.6
|
5.6
|
5.6
|
0.896
|
|
II
|
63
|
27
|
74.9
|
53.7
|
51.0
|
18.0
|
39.0
|
41.6
|
2.2
|
7.3
|
7.3
|
|
III
|
88
|
39
|
55.2
|
40.0
|
27.3
|
35.7
|
48.0
|
60.6
|
9.2
|
12.1
|
12.1
|
- CHCC combined hepatocellular cholangiocarcinoma, LN lymph node, TNM Tumor-Node-Metastasis
