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Table 5 Hazard ratios and 95% confidence intervals for overall mortality, according to subtype admixture of Luminal A breast cancers in the METABRIC cohort

From: Quantification of intrinsic subtype ambiguity in Luminal A breast cancer and its relationship to clinical outcomes

 

Unadjusted

Adjusteda

HR

95% CI

HR

95% CI

Median Distance

 Pure

1.00

–

1.00

–

 Neither

1.48

1.10–2.00

1.12

0.83–1.53

 Admixed

1.93

1.42–2.63

1.47

1.07–2.02

Distance Ratio

 Tertile 1

1.00

–

1.00

–

 Tertile 2

1.45

1.11–1.91

1.20

0.91–1.59

 Tertile 3

1.98

1.52–2.58

1.42

1.07–1.88

 

Ptrend = < 0.001

Ptrend = < 0.001

  1. aAdjusted for age, grade, stage and tumor size