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Fig. 7 | BMC Cancer

Fig. 7

From: Zoledronic acid blocks the interaction between breast cancer cells and regulatory T-cells

Fig. 7

Treatment with ZA affects gene expression profile in MDA-MB-231cells and IFN-γ activated MDA-MB-231cells. a-b The human global gene expression profiles of two independent RNA samples were analyzed by human oligonucleotide DNA microarray at 48 h post-transfection. c Corrected microarray signal values of genes involved in different biological process, clustered by Biological process of MDA-MB-231 cells treated for 24 h with 25 μM ZA in comparison to control cells. d Corrected microarray signal values of genes involved in different biological process, clustered by Biological process of IFN-γ activated MDA-MB-231 cells treated for 24 h with 25 μM ZA in comparison to control cells. e Of the genes commonly down-regulated by ZA in MDA-MB-231cells and IFN-γ activated MDA-MB-231cells. f Of the genes commonly down-regulated by ZA in MDA-MB-231cells and IFN-γ activated MDA-MB-231cells

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