Table 1 Reported cases of synchronous co-existing of PTC and LCH in the thyroid gland
Author/Year | Sex/Age | PTC&LCH In Thyroid | Side | LCH in other organs | Treatment | BRAF mutations | Follow up (months) |
|---|---|---|---|---|---|---|---|
Goldstein N, 1991 [9] | F/31 | Yes | Left | Bone, Pituitary gland, Lung, Skin, Vagina | Surgery, Prednisone, Vincristine, Methotrexate, Chlorambucil | NR | DF (6) |
Saiz E, 2000 [10] | M/43 | Yes | Left | No | Surgery | NR | DF(24) |
Foulet-Roge A, 2002 [11] | F/42 | Yes | Left | No | Surgery | NR | DF (14) |
Burnett A, 2008 [12] | M/3 | LCH in Right, PTC in Left | Bilateral | Lung | Surgery, Prednisone, Mercaptopurine, Methotrexate | NR | NR |
Jamaati HR, 2009 [13] | M/24 | Yes | Bilateral | Lung | Surgery, Etoposide, Dexamethasone | NR | DF(NR) |
Vergez S, 2010 [1] | M/29 | Yes | Bilateral | Bone, Pituitary gland, Lung, Skin | Corticosteroids, Vinblastine, Cladribine, Imatinib | NR | DRD(36) |
Chung DH, 2012 [2] | F/53 | Yes | Right | NR | Surgery | NR | NR |
Ceyran AB, 2014 [14] | M/37 | Yes | Bilateral | NR | Surgery | NR | Died due to Cardiac arrest |
Gordon M S, 2016 [16] | F/22 | Yes | Bilateral | Labia Vulva | Surgery, Prednisone | V600E in PTC | NR |
Alzahrani R, 2016 [7] | F/27 | Yes | Bilateral | No | Surgery, CT Prednisone | NR | NR |
Wu X, 2017 [8] | M/40 | Yes | Right | Lung, Liver | Surgery, CT | NR | DF(24) |
Jaimanti Bakshi JK,2018 [15] | M/31 | Yes | Right | No | Surgery, Vinblastine and Etoposide | NR | NR |
Current case | F/37 | Yes | Bilateral | No | Surgery, Prednisone with Etoposide | V600E in PTC,V600K in LCH | DF (12) |