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Table 1 Patient characteristics in this study (n = 192)

From: Efficacy and risk of cytotoxic chemotherapy in extensive disease-small cell lung cancer patients with interstitial pneumonia

 

Without IP

With IP

P*

n = 152

n = 40

Age, median (range), years, n (%)

71 (42–95)

73 (47–83)

0.82

 < 75 years

98 (64.5)

25 (62.5)

 ≥75 years

54 (35.6)

15 (37.5)

Gender, n (%)

 Male

126 (82.9)

37 (92.5)

0.13

 Female

26 (17.1)

3 (7.5)

Smoking status, n (%)

 Never

8 (5.5)

2 (5.0)

0.94

 Former/Current

139 (91.4)

37 (92.5)

ECOG PS, n (%)

 0/1

80 (52.6)

20 (50.0)

0.77

 2/3/4

72 (47.4)

21 (50.0)

Blood tests, mean ± SD

 Alb, g/dL

3.6 ± 0.5

3.6 ± 0.4

0.35

 LDH, IU/L

476.7 ± 778.4

391.5 ± 293.5

0.72

 CRP, mg/dL

3.0 ± 5.0

3.3 ± 5.5

0.45

 KL-6, U/mL

437.2 ± 480.3

832.0 ± 701.2

< 0.001

 SP-D, U/mL

62.6 ± 47.6

141.0 ± 91.0

0.005

  1. * p-values were analyzed by the χ2 test
  2. Note: IP interstitial pneumonia, PS performance status, SD standard deviation, Alb albumin, LDH lactate dehydrogenase, CRP C-reactive protein, KL-6 Krebs von den Lungen-6, SP-D pulmonary surfactant protein-D